The findings of this review are encouraging; suggesting that osteopathic treatment may have some effects on anxiety, fear avoidance, quality of life and general health status in populations living with persistent pain.

Two studies out of five reported significant differences in depression; in regards to anxiety, all the four trials found significant effects; two out of three trials reported a significant reduction in fear avoidance while six out of seven trials found a significant enhancement of health status and three out of four found an increase in quality of life. 

Saracutu, M., Rance, J., Davies, H., & Edwards, D. (2018). The effects of osteopathic treatment on psychosocial factors in people with persistent pain: A systematic review. International Journal of Osteopathic Medicine, 27, 23-33.


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